Efficacy of Repeated Locoregional Anesthetics Blocks With Bupivacaine in Patients Suffering of Chronic Dentoalveolar Pain.

• Status: Recruiting
• Trial end date: 2023-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to evaluate the efficacy of anesthetic blocks repeated with bupivacaine in the management of patients with persistent dentoalveolar pain. Goals are to improve the understanding of the physiopathological mechanisms of persistent dentoalveolar pain and to highlight predictive criteria for the effectiveness of anesthetic blocks.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Clermont-Ferrand
• Treatments: Anesthetics; Bupivacaine; Lidocaine

Criteria

Inclusion Criteria:

• Patient, male or female, over 18, with persistent dentoalveolar pain defined according to the criteria:

• daily presence (> 2 hours / day and for more than 3 months) and continues pain;

• located at one or more teeth or at the level of the alveolar bone;

• not following a nervous path;

• clinical, radiological and neurological examinations showing no cause organic visible;

• dental causes excluded by appropriate tests;

• local or systemic pathologies related to pain apart.

• Pain intensity greater than or equal to 4/10 on numerical scale

• Patient informed of the constraints of the study and having given his written consent. Benefiting of a social security scheme.

• Mastering correctly French.

Exclusion Criteria:

• Pregnant women, breastfeeding, or likely to be pregnant.

• Oral pain of known origin (cancerous, infectious, traumatic).

• Patient having modified (stopped, started or modified dosage) in the last 2 month local or systemic medication that may interfere with the study results (for example, patients taking long-range psychotropic drugs will not be excluded).

• All medical pathology judged by the investigator as not compatible with the study.

• Known hypersensitivity to local amide-bound anesthetics or to any of the excipients

• Treatment anticoagulant or known disorder of blood

• Porphyria.

• Atrioventricular conduction requiring training permanent electrosystol not yet realized.

• Epilepsy not controlled by a treatment.

• Patient non-cooperating, not speaking or not reading fluently French or in the impossibility of understanding the principle of a pain scale or understanding the study or to sign an informed consent.

• Patient under guardianship, curatorship, or deprived of liberties.