Efficacy of Prevention for Postoperative Nausea and Vomiting After Intrathecal Morphine in Cesarean Section

• Status: Unknown status
• Trial end date: 2011-04-01
• Target enrollment: 0
• Participant gender: Female

Summary

Post-operative nausea and vomiting are the major complications after spinal anesthesia with intrathecal morphine, therefore antiemetic drugs should be administered for best satisfaction of anesthesia to prevent these complication.

Furthermore, administration of a combination of antiemetic drugs with different mechanisms of action appears reasonable and synergistic effect of drugs.

In conclusion, we study efficacy of antiemetic effect of single antiemetic drug compare with combination antiemetic drugs.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Mahidol University
• Treatments: BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Metoclopramide; Morphine; Ondansetron

Criteria

Inclusion Criteria:

• Pregnancy patients undergo Elective cesarean section age more than 18 years

• Patient accept spinal anesthesia technique

• ASA classification I-II

• Patient understand question and evaluation process

Exclusion criteria:

• Hyperemesis gravidarum

• Patient ongoing treatment with antiemetic drugs

• Allergy to Metoclopramide,Ondansetron and Dexamethasone