Efficacy of Polyethylene Glycol vs Lactulose With Isabgol in Acute Fissure-in-Ano: A RCT (PEGASIS Trail)
Status:
Not yet recruiting
Trial end date:
2023-12-31
Target enrollment:
Participant gender:
Summary
The existing literature stresses the better efficacy of polyethylene glycol (PEG) over other
stool softeners like lactulose or isabgol to improve functional constipation.
But there is no consensus regarding the efficacy of PEG alone vs lactulose combined with
isabgol used as stool softeners, frequently used for relieving acute constipation in an acute
fissure in ano. Hence a good quality randomised study to compare both efficacies is the need
of the hour.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
All India Institute of Medical Sciences, Bhubaneswar