Efficacy of Perioperative Duloxetine as a Part of Multimodal Analgesia in Laparoscopic Colorectal Cancer Surgery

• Status: Not yet recruiting
• Trial end date: 2021-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Our aim will be to evaluate the efficacy of perioperative Duloxetine in decreasing acute postoperative pain after laparoscopic colorectal cancer surgery and its role in reducing postoperative morphine requirements

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Assiut University
• Treatments: Duloxetine Hydrochloride

Criteria

Inclusion Criteria:

• ASA I-III

• aged 18-65 years and scheduled for laparoscopic colorectal surgery for cancer colon

Exclusion Criteria:

• unable to express their pain or patient refusal.

• allergy to the study drug

• an abnormal liver or renal function tests

• a chronic opioid abuser(> 3 mo), being on chronic gabapentin or pregabalin(> 3 mo)

• antidepressant drugs, patients with psychiatric disorders

• Pregnant females