Efficacy of Para-Tyrosine Supplementation on the Survival and Clinical Outcome in Patients With Sepsis
Status:
Not yet recruiting
Trial end date:
2024-02-28
Target enrollment:
Participant gender:
Summary
Meta-and ortho-Tyrosine are known markers of oxidative stress, while the physiological
isomer, para-Tyrosine is suggested the antagonize the effects of meta- and ortho-Tyrosine.
The changes in the serum levels of meta- and ortho-Tyrosine have been found to be paralel to
that of the common sepsis markers. The hypothesis of the study is, that supplementation of
para-Tyrosine (p-Tyr) in the early phase of sepsis may diminish some specific inflammatory
procedures and thus may have a favourable impact on the disease progress, and consequently on
the mortality.