Efficacy of Oral Versus Intravenous Acetaminophen for Primary Pediatric Cleft Palate Repair
Status:
Completed
Trial end date:
2014-08-01
Target enrollment:
Participant gender:
Summary
The purpose of this investigator-initiated study is to determine whether acetaminophen is an
effective pain reliever for primary cleft palate repair in children and possesses opioid
sparing effects. Additionally, the investigators will determine if patients who receive
acetaminophen have less opioid related side-effects. The study will have three study groups
based on whether the patient receives Ofirmev® and opioids (Fentanyl and Morphine), oral
acetaminophen elixir and opioids (Fentanyl and Morphine), or opioids (Fentanyl and Morphine)
alone. Total opioid (Fentanyl and Morphine) consumption will be tracked for the
intraoperative period and 24 hours after surgery for all patients within the study and
converted to morphine equivalents.