Efficacy of Multimodal Peri- and Intraarticular Drug Injections in Total Knee Arthroplasty

• Status: Completed
• Trial end date: 2009-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Total knee arthroplasty (TKA) is associated with moderate to severe postoperative pain, causing patient discomfort, mobilisation and hospital discharge.

The aim of this study is to:

1. Compare analgetic efficacy of to types of local infiltration analgesia in total knee arthroplasty.

2. Compare analgetic efficacy of local infiltration analgesia with continuous epidural analgesia.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Asker & Baerum Hospital
• Treatments: Bupivacaine; Epinephrine; Epinephryl borate; Fentanyl; Ketorolac; Ketorolac Tromethamine; Morphine; Racepinephrine; Ropivacaine

Criteria

Inclusion Criteria:

• patients at least 18 years of age

• scheduled for elective total knee arthroplasty

• ASA I-III

• signed written informed consent

Exclusion Criteria:

• age < 18

• ASA > III

• moderate or severe cardiac disease, bronchial asthma

• allergy against ropivacaine, ketorolac or morphine

• analgetic abuse

• pregnancy or nursing women

• severe psychiatric disease

• moderate to severe dementia