Efficacy of Metformin in PCOS: Metabolic and Hormonal Factors
Status:
Unknown status
Trial end date:
2004-09-01
Target enrollment:
Participant gender:
Summary
Hypothesis: Metformin treatment normalises hormone values and metabolic parameters in women
with PCOS. Ovulation is restored and bleeding periods become regular.
Fifty women with PCOS (Rotterdam criteria) are randomised to either placebo or metformin for
6 months. After a wash-out period of 3 months, the opposite treatment is given for another 6
months. Measurements are performed before ech treatment period, every second month during
treatment and after completing treatment.
Phase:
N/A
Details
Lead Sponsor:
Aarhus University Hospital Skejby
Collaborators:
Aarhus University Hospital Regional Hospital Holstebro