Efficacy of Macrolide and Glucocorticoid in the Treatment of Chronic Rhinosinusitis After Endoscopic Sinus Surgery
Status:
Completed
Trial end date:
2016-06-01
Target enrollment:
Participant gender:
Summary
Endoscopic sinus surgery (ESS) is widely considered to be the gold standard in the surgical
management of chronic rhinosinusitis (CRS) that has failed maximal medical therapy.
Nevertheless, the postoperation medical therapy was considered as a crucial procedure for the
success of ESS. Both glucocorticoids and macrolide antibiotics have been recommended for the
treatment of CRS, but their effect as postoperation medical therapies of ESS need more
clinical data to clarify.
The purpose of this prospective, randomized,study is to determine the effect of
glucocorticoids and macrolide antibiotics for the postoperation medical therapy of ESS in
different subtypes of CRS.