Efficacy of Loperamide for C. Difficile Colitis and Other Diarrheal Diseases Associated With Antibiotic Therapy

• Status: Suspended
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

To determine whether symptomatic treatment of the diarrhea in CDAD reduces morbidity and mortality of this serious nosocomial infection in patients who have antibiotic-associated diarrhea. Both C. diff positive and negative patients will be included.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Michael E. DeBakey VA Medical Center; VA Medical Center, Houston
• Treatments: Anti-Bacterial Agents; Antibiotics, Antitubercular; Antidiarrheals; Loperamide

Criteria

Inclusion Criteria:

• Patients with diarrheal stools considered to be antibiotic associated

Exclusion Criteria:

• Inability of sign consent

• Patient with other known gastrointestinal disease

• Patients receiving tube feeding or fecal incontinence prior to receiving antibiotics