Efficacy of Irinotecan and Capecitabine Versus(vs) Cisplatin and Capecitabine in Patients With Esophago-Gastric Cancer

• Status: Completed
• Trial end date: 2007-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine which Arm (capecitabine + irinotecan versus capecitabine + cisplatin) shows higher response rates in the treatment of advanced gastric-oesophagal cancer

Furthermore, comparison of progression-free survival, 1-year survival, Quality of Life and safety

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Johannes Gutenberg University Mainz
• Treatments: Camptothecin; Capecitabine; Cisplatin; Irinotecan

Criteria

Inclusion Criteria:

• gastric or gastric-oesophagal junction adenocarcinoma

• unidimensional measurable disease

• Karnofsky index >/=60%

Exclusion Criteria:

• prior chemo- or radiotherapy

• colorectal diseases

• brain metastases