The investigators' goal in this planned prospective, randomized, patient blinded study is to
compare our standard of care as the control group to an experimental group in which patients
receive preemptive IV acetaminophen dosing that is continued every 6 hours for a total of 8
doses in patients who have undergone major gynecologic surgery. The outcomes analyzed will
include amount of rescue opioids required, time to return of bowel function, length of
hospital stay, and patient satisfaction. The hypothesis is that the addition of IV
acetaminophen will decrease the need for opioid rescue and thereby decrease the incidence of
associated gastrointestinal side effects including nausea, vomiting, bloating, and
constipation. The hope is that it will affect the final outcome of quicker return of bowel
function, increased patient satisfaction, shortened hospital stay and prove to be an overall
more effective postoperative pain management approach.
Phase:
Phase 4
Details
Lead Sponsor:
Aultman Health Foundation
Treatments:
Acetaminophen Acetaminophen, hydrocodone drug combination Anesthetics