Overview

Efficacy of High-dose Dual Therapy vs Bismuth-containing Quadruple Therapy for Rescue Treatment of Hp Infection

Status:
Completed
Trial end date:
2019-01-01
Target enrollment:
Participant gender:
Summary
Up to now, there is few randomized, large scale study prospectively and simultaneously comparing the efficacy, adverse effects and patient adherence of high-dose dual therapy (HDDT) and bismuth-containing quadruple therapy (BQT) as rescue regimens for H. pylori eradication. The aims of this study are: 1. to compare the efficacy of HDDT, and BQT as rescue regimen in H. pylori eradication; 2. to compare the patient adherence and adverse effects of these treatment regimens; 3. to investigate factors that may influence H. pylori eradication by these treatment regimens.
Phase:
Phase 4
Details
Lead Sponsor:
National Taiwan University Hospital
Treatments:
Amoxicillin
Anti-Bacterial Agents
Antibiotics, Antitubercular
Bismuth
Metronidazole
Proton Pump Inhibitors
Rabeprazole
Tetracycline