Efficacy of Gabapentin vs. Placebo for Adjuvant Pain Control Following Acute Rib Fractures

• Status: Completed
• Trial end date: 2018-10-23
• Target enrollment: 0
• Participant gender: All

Summary

A Multi-center, Randomized Controlled Trial of the Efficacy of Gabapentin vs. Placebo for Adjutant Pain Control Following Acute Rib Fractures.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Denver Health and Hospital Authority
• Collaborator: University of Colorado, Denver
• Treatments: Gabapentin; gamma-Aminobutyric Acid

Criteria

Inclusion Criteria:

• > 1 rib fractures

• Requiring hospital admission

• Enrolled within 24 hours of injury

Exclusion Criteria:

• Pregnancy

• Intubation

• Age <18, age >65

• Inability to tolerate PO medication

• Patient refusal

• Inability to obtain consent from patient or surrogate

• Renal or Hepatic impairment

• Allergy or Hypersensitivity to gabapentin or any component of the formulation