Efficacy of Doxycycline in the Treatment of Early Stages of Mycosis Fungoides

• Status: Unknown status
• Trial end date: 2019-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Current study aims at assessing the efficacy of doxycycline as a potential treatment modality for early stages of MF.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cairo University
• Treatments: Doxycycline

Criteria

Inclusion Criteria:

• Adults (above 18) of either sex with established diagnosis of classic MF

Exclusion Criteria:

• Any variant of MF other than the classic variant.

• Advanced stages of classic MF: Stage IIb, III or IV.

• Pregnant and lactating females.

• Patients with autoimmune diseases e.g. SLE

• Patients with solid or hematological malignancies e.g. breast cancer, leukemia, etc.

• Patients with any contraindications for doxycycline (eg: liver disease, kidney disease, photosensitivity, peptic ulcer or patients receiving systemic retinoids).

• Patients with any contraindication to phototherapy (eg: any other skin cancers or photosensitivity); or to psoralen (eg: liver disease)