Efficacy of Diclofenac Suppository for Pain Control in Ultrasound Guided Biopsy of Prostate
Status:
Completed
Trial end date:
2012-10-01
Target enrollment:
Participant gender:
Summary
Transrectal ultrasound guided biopsy of prostate (TRUS-Bx) is widely used as accepted mode of
investigation for prostate cancer in current urology practice. It is considered a minor
procedure, which most of the patients tolerate, however 20% of patients refuse to undergo the
redo procedure without any analgesia or anesthesia but on the other hand, some authors reveal
that 65 to 90% of patients report pain ranging from mild to severe in intensity. Diclofenac
is a local and systemic anti-inflammatory drug and it reduces local mediators involved in
local pain.The purpose of this study is to find out the role of rectal administration of
diclofenac suppositories as an adjunct to 2% xylocaine gel in alleviating intra and post
procedural pain in prostatic biopsy with adequately calculated sample size and excluding the
patients with contraindication to procedure or diclofenac administration as these were the
shortcomings of previous studies.