Efficacy of Dexamethasone or Adrenaline in Inferior Alveolar Nerve Block
Status:
Completed
Trial end date:
2021-02-28
Target enrollment:
Participant gender:
Summary
Oral and dental professionals were responsible for the discovery of anaesthesia, given their
close day-to-day contact with pain and, hence, their motivation to seek the means to
alleviate it. Currently, third molar surgery (TMS) has become the model most frequently used
in acute pain trials because third molar surgery (TMS) is simple and frequently used
procedure with pain moderate or severe in intensity, as well as sufficient numbers of
patients, are available for the required sample size for the studies.
Effective local anaesthesia is arguably the single most important pillar upon which modern
dentistry stands. Many agents are not available in the markets of Nepal that provide a rapid
onset of surgical anaesthesia with adequate duration. The current study is designed to search
for a better quality of perioperative analgesics with a single injection of dexamethasone and
lignocaine in IANB preoperatively during TMS. The purpose of the current study is to evaluate
the effectiveness and safety profiles of coadministration of dexamethasone (4mg/ml) or
adrenaline ( 0.01mg/ml) with lignocaine 2% in IANB during TMS. Best of my knowledge this is a
unique and novel clinical trial, probably the first trial which aim to overcome three
principal challenges of local anaesthesia with a single injection during TMS.