Efficacy of Dexamethasone in Treatment of Meconium Aspiration Syndrome

• Status: Completed
• Trial end date: 2021-06-30
• Target enrollment: 0
• Participant gender: All

Summary

Objective: To determine efficacy of dexamethasone in treatment of meconium aspiration syndrome.

Study design: Randomized control trial. Place and duration: Services hospital, Neonatal unit, Lahore. During time span of 1st January to 30th June 2021.

Material and methods Total 100 neonates were randomly divided in two groups. Group A (n=50) was treated with dexamethasone (Cases) and Group B (n=50) served as control. Dexamethasone was given in dose of 0.2mg/kg, 12 hourly for 7 days after confirmation of diagnosis. Infants present in clinical trial were evaluated by ventilation duration (invasive and non-invasive), oxygen therapy and hospital stay.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Services Institute of Medical Sciences, Pakistan
• Treatments: BB 1101; Dexamethasone; Dexamethasone acetate

Criteria

Inclusion Criteria:

1. Term and Post-Term babies who met the operational definition of MAS (inborn)

2. Presenting within 24 hours of life

Exclusion Criteria:

1. Preterm babies or babies with congenital malformations

2. Preterm babies or babies with dysmorphism

3. Preterm babies or babies with hypoxic-ischemic encephalopathy