Efficacy of Combination Therapy With Minocycline for Treatment of Stenotrophomonas Maltophilia Infections

• Status: Not yet recruiting
• Trial end date: 2024-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective of the study is to evaluate the efficacy of minocycline for treatment Stenotrophomonas maltophilia infection. The hypothesis of study is the combination therapy with minocycline would be better than the monotherapy for treatment Stenotrophomonas maltophilia infection.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mahidol University
• Treatments: Minocycline

Criteria

Inclusion Criteria:

• The infection caused by Stenotrophomonas maltophilia

• The duration of treatment approximately between 7-28 days

• The patients can take minocycline capsule via oral or nasogastric tube feeding.

• The patients are anticipated to live more than 48 hrs after participation.

• In case of an antibiotic drug administration for treatment Stenotrophomonas maltophilia beforehand, it should not exceed 48 hrs.

• All of participants should be willing to join this project.

Exclusion Criteria:

• Pregnancy and lactation

• The patients with active hepatitis

• The patients with history of minocycline allergy