Efficacy of Caffeine Injection as an Adjuvant to Opioid Therapy in Cancer Pain
Status:
Completed
Trial end date:
2009-09-01
Target enrollment:
Participant gender:
Summary
Pain is a most common symptom and it has a high impact on quality of life in cancer patients.
Many cancer patients have received opioid therapy, but also many of them have suffered from
side effects of opioids. Drowsiness and confusion are common side effects of opioids.
Caffeine is a well known psychostimulant,and it is widely used as an analgesics. Thus, the
investigators aimed to prove the efficacy of intravenous caffeine administration as an
adjuvant analgesics to opioids. At the same time, the investigators tried to find that the
side effects of opioids could be ameliorated by caffeine.
Phase:
Phase 2
Details
Lead Sponsor:
Korea Research Foundation
Collaborator:
Korea University Guro Hospital
Treatments:
Caffeine Caffeine, sodium benzoate drug combination Sodium Benzoate