Efficacy of CPP-ACP on Bleaching Related Sensitivity
Status:
Completed
Trial end date:
2007-03-16
Target enrollment:
Participant gender:
Summary
Objective: The purpose of this randomized controlled split-mouth clinical trial was to
evaluate the effectiveness of MI paste in reducing sensitivity associated vital bleaching.
Methods: 45 subjects were randomly divided into two groups, based upon which arch received MI
Paste. Group 1 bleached Maxillary arch, Group 2 bleached mandibular arch. Two weeks later
subjects stopped bleaching the first arch and started second arch. Sensitivity was measured
by VAS daily log scale for two weeks. Shade was taken with colorimeter and Classic Vita shade
guide at baseline, immediate post-bleaching, and two weeks post-bleaching. Longitudinal
sensitivity over the 14 days period of bleaching was summarized. The Wilcoxon Signed Rank
test was used to compare summary measures.