Efficacy of Artemether/Lumefantrine for the Treatment of Uncomplicated Malaria.
Status:
Completed
Trial end date:
2013-08-01
Target enrollment:
Participant gender:
Summary
Artemether-lumefantrine has been used in Tanzania as first-line treatment for uncomplicated
malaria since 2007. Nonetheless, a report of increased proportion of patients with
parasitaemia on day 1 following treatment with artemisinin based combination therapies has
emerged from Kenya. Similarly, resistance against artemisinins has been confirmed in
South-East Asia and it can spread to Africa. Therefore, the purpose of this study was to
assess the efficacy of Artemether-lumefantrine for the treatment of uncomplicated malaria
among children after five years of wide scale use of the drug in Tanzania.
Phase:
Phase 4
Details
Lead Sponsor:
Richard Mwaiswelo
Collaborator:
Karolinska Institutet
Treatments:
Artemether Artemether-lumefantrine combination Artemether, Lumefantrine Drug Combination Artemisinins Lumefantrine