Overview
Efficacy of Antiviral Therapy in Pregnancy in Preventing Vertical Transmission of HBV in Mothers With a High Viral Load
Status:
Unknown status
Unknown status
Trial end date:
2015-12-01
2015-12-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
Mother-to-child transmission (MTCT) is the most common route of hepatitis B virus (HBV) infection. After given standard immunoprophylaxis, MTCT still occurred in some infants born to a HBsAg positive mothers with high HBV DNA load. The main purpose of this study is evaluating the efficacy of methods used in blocking MTCT of HBV in infants born to a HBsAg positive mothers with high serum HBV DNA loads.Accepts Healthy Volunteers?
NoDetails
Lead Sponsor:
Beijing Ditan HospitalTreatments:
Antiviral Agents
Telbivudine
Criteria
Inclusion Criteria:- infants born to HBsAg positive mother HBsAg positive mother
Exclusion Criteria:
- mothers coinfected HIV or HCV