Efficacy of Antiresorptive and Bone Forming Material on Dental Implants
Status:
Unknown status
Trial end date:
2020-07-01
Target enrollment:
Participant gender:
Summary
Insertion of a metal implant is considered one of the most common surgeries for fracture
treatment, joint replacement, and dental implants. The success rate of these implants depends
on their fixation which is in turn related primarily on the strength of the bone holding
them. Studies evaluating the influence of local application of antiresorptive drugs, like
bisphosphonates, on implanted endoprostheses whether orthopedic or dental is increasing
annually with more and more experimental studies as well as clinical trials worldwide. On the
other hand implants that release medications that enhance bone formation will lead to
improved implant fixation and success. The objective of this study was to evaluate the effect
of topical application of alendronate sodium gel and recombinant human bone morphogenic
protein 2 on dental implant stability and crestal bone level.