Efficacy of Anthocyanin Mouthrinse for Oral Anti-inflammation From Orthodontic Treatment

• Status: Completed
• Trial end date: 2016-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare the oral inflammatory reduction effect caused from orthodontic treatment of anthocyanin and placebo mouthrinse.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Khon Kaen University

Criteria

Inclusion Criteria:

• Male and/or females between the ages of 18 and 35 with oral inflammation, investigated by a dentist, caused by orthodontic devices.

• The inflammatory lesions are occurred at labial and/or buccal mucosa.

• Be able to communicate well with the investigator and to comply with the requirements of the entire study.

• Not participate in other project(s).

• Be willingness to give written informed consent (prior to any study-related procedures being performed) and to be able to adhere to the study restrictions and examination schedule.

Exclusion Criteria:

• - Have the persistent inflammatory lesions and/or ulcers that cannot be healed more than 2 weeks or the inflammation that may lead to be oral cancer.

• Have severe oral inflammation or the inflammation occur from ongoing head and neck chemotherapy or serious oral inflammatory such as periodontitis and oral lichen planus.

• Taking steroid or applying topical steroid within or 7 days before participated in this study.

• Have a history of allergy or hypersensitivity to any red, blue, or purple color fruits and vegetables such as berry groups.

• Patients with auto-immune diseases or diseases that related to wound healing process such as diabetes.

• Patients that cannot meet the follow up or drop out of the experiments.