Efficacy of 25% Trichloroacetic Acid Peel Versus 30% Salicylic Acid Peel in Mild to Moderate Acne Vulgaris

• Status: Completed
• Trial end date: 2022-11-30
• Target enrollment: 0
• Participant gender: All

Summary

To compare the efficacy of 25% trichloroacetic acid peel versus 30% salicylic acid peel in mild to moderate acne vulgaris.

Study Design: Randomized Control Trial. Place And Duration of Study: Department of Dermatology, CMH Abbottabad from 01 Jun 2022 to 30th Nov, 2022.

Methodology: A total of 60 patients presented with mild or moderate acne vulgaris were randomized into two groups comprising 30 patients in each group and treated with either the TCA peel or the SA peel at 2-week intervals for 12 weeks. Patients in Group A were treated with 25% TCA peel whereas patients in Group B were treated with 30% SA peel. At the end of therapy after 12 weeks, evaluation of active acne was done by individual lesion counts (comedones, papules and pustules) and calculation of the Michaelsson acne score (MAS).

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Combined Military Hospital Abbottabad
• Treatments: Salicylates; Salicylic Acid

Criteria

Inclusion Criteria:

• Patients with mild or moderate facial acne vulgaris presented in dermatology opd

Exclusion Criteria:

• Patients with grade III or IV acne vulgaris

• patients taking any acne medications or had taken oral or topical medications in the past 4 weeks

• pregnant female patients or nursing a baby

• patients with known hypersensitivity to the formulations used in the study or a history of photosensitivity

• hypertrophic scars, keloidal tendency, active or recurrent herpes simplex infection

• active dermatosis

• unrealistic expectations