Efficacy and Safety of WPQW Granule for Overlap of NERD and IBS-D
Status:
Recruiting
Trial end date:
2023-05-01
Target enrollment:
Participant gender:
Summary
Non-erosive reflux disease（NERD）and Diarrhea-Predominant Irritable Bowel Syndrome（IBS-D）are
both the common refractory gastrointestinal diseases. Patients, who suffered from overlapping
symptoms of NERD and IBS-D, present more serious symptom manifestation, anxiety, and worse
life quality than those with solely disease. There is lack of effective treatment for
overlapping gastrointestinal symptoms. Traditional Chinese Medicine (TCM) syndrome
differentiation and treatment has the advantages of overall regulation and individualized
treatment, but lack of high-level evidence. The purpose of this study is to evaluate the
efficacy and safety of WPQW granule for the treatment of NERD overlapping IBS-D.
Phase:
Early Phase 1
Details
Lead Sponsor:
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Collaborators:
The First Affiliated Hospital of Henan University of Traditional Chinese Medicine the first affiliated hospital of Liaoning university of traditional Chinese medicine The First Affiliated Hospital of Shanxi University of Traditional Chinese Medicine Tianjin Nankai Hospital Yunnan Provinical Hospital of Traditional Chinese Medicine