Efficacy and Safety of Vitamin D in the Treatment of OAB-wet in Children
Status:
RECRUITING
Trial end date:
2024-10-15
Target enrollment:
Participant gender:
Summary
The purpose of this clinical trial is to investigate whether standard behavioral therapy combined with high-dose vitamin D (2400iu daily) is superior to standard behavioral therapy alone and standard behavioral therapy combined with solifenacin medication in improving frequency of incontinence and lower urinary tract symptom scores in children with wet OAB. Dedicated to understanding the current best treatment for wet OAB and to informing future clinical decisions and improving patient prognosis. The main questions it seeks to answer are
* Question 1 To attempt to elucidate the relationship between vitamin D levels and their lower urinary tract symptoms.
* Question 2 To examine the etiologic role of vitamin D in wet OAB in children.
* Question 3 Compare the effectiveness and safety of interventions to elucidate the etiologic mechanisms and optimal intervention strategies for wet OAB in children.
The researchers will compare (1) standard behavioral therapy with solifenacin (2) standard behavioral therapy with high-dose vitamin D (3) standard behavioral therapy alone to observe the clinical efficacy and safety of the three interventions for children with wet OAB.