Overview

Efficacy and Safety of Unfractionated Heparin on Severe Sepsis With Suspected Disseminated Intravascular Coagulation

Status:
Unknown status

Trial end date:
2021-06-01

Target enrollment:

Participant gender:

Summary

The primary objective of this study is to estimate the efficacy of unfractionated heparin(UFH) on ICU mortality in severe sepsis with suspected DIC.The Second objective is to estimate the effect of UFH on 28-day mortality,and the change of the Japanese Association for Acute Medicine(JAAM) score and SOFA score. The third one is to evaluate the safety of UFH in severe sepsis patients with suspected DIC.

Phase:

Phase 3

Details

Lead Sponsor:

China Medical University, China

Collaborators:

Central South University
First Affiliated Hospital, Sun Yat-Sen University
Peking Union Medical College Hospital
Shengjing Hospital
The First Affiliated Hospital of Dalian Medical University
The Second Affiliated Hospital of Harbin Medical University
West China Hospital
Zhejiang Hospital
Zhongda Hospital

Treatments:

Calcium heparin
Heparin