Efficacy and Safety of Sodium Oligomannate in the Prevention of PSCI
Status:
Not yet recruiting
Trial end date:
2023-12-31
Target enrollment:
Participant gender:
Summary
Post-stroke cognitive impairment (PSCI) is a common complication of stroke, and seriously
affect the quality of survival and the survival time in patients with stroke, PSCI is still
lack of effective prevention and treatment measures, the study found that gut microbiota are
closely associated with stroke and cognitive diseases, sodium oligomannate can improve
cognitive function of mild-to-moderate alzheimer's disease (AD) , The Expert Consensus 2021
on the Management of Post-stroke cognitive impairment states that the role of sodium
oligomannate in PSCI needs to be investigated in large sample clinical trials. This study
intends to explore the efficacy and safety of sodium oligomannate in the prevention of PSCI
in patients with acute ischemic stroke and cognitive impairment, so as to provide a potential
intervention for the prevention of PSCI.