Efficacy and Safety of Silodosin in the Treatment of Natural Expulsion in Patients With Ureteral Stones
Status:
Completed
Trial end date:
2012-08-01
Target enrollment:
Participant gender:
Summary
A lower ureteral calculus, which measures 5 millimeters and less, may be easily expelled by
symptomatic therapy. Actually, it has about a 50% chance of successful expulsion.
However, a complication such as urinary tract infection or hydronephrosis or persistent pain
may occur before it is expelled. Thus, it is imperative to minimize the occurrence of
complications in the process of expectant treatment and also to reduce the time required to
expel calculi.
Pharmacotherapy is to relieve ureteral obstruction and thus to expel urinary calculi easily.
This clinical trial is to evaluate the efficacy of silodosin, a selective α1A-blocker, on
calculous expulsion in expectant treatment for patients with lower and mid ureteral calculi.