Efficacy and Safety of Prophylactic Use of an Antibiotic for Medical Thoracoscopy

• Status: Completed
• Trial end date: 2016-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a prospective study to assess the efficacy and safety of a single dose of cefazolin 2g IV for the prophylaxis of surgical site and pleural space infections in patients undergoing medical thoracoscopy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Postgraduate Institute of Medical Education and Research
• Treatments: Anti-Bacterial Agents; Antibiotics, Antitubercular; Cefazolin; Clindamycin; Clindamycin palmitate; Clindamycin phosphate

Criteria

Inclusion Criteria:

1. Age ≥12 years

2. Medical thoracoscopy being performed for a pleural effusion for any of the three indications: diagnosis, pleurodesis, or adhesiolysis

Exclusion Criteria:

1. Age ≥80 years

2. Pao2/FIO2< 300;

3. Hemodynamic instability

4. Myocardial infarction or unstable angina in the last 6 wk

5. Lack of pleural space due to adhesions

6. Uncorrected coagulopathy

7. Failure to provide informed consent

8. Patients already taking any antibiotic due to any reason