Efficacy and Safety of Oral Versus Intravenous Ibuprofen for PDA Treatment in ELBW Infants

• Status: Completed
• Trial end date: 2011-06-01
• Target enrollment: 0
• Participant gender: All

Summary

To determine whether oral or intravenous ibuprofen has a better or same efficacy and tolerance in closure of patent ductus arteriosis in extremely-low-birth-weight preterm infants.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Zekai Tahir Burak Women's Health Research and Education Hospital
• Treatments: Ibuprofen

Criteria

Inclusion Criteria:

• Birth weight below 1000 gram

• Diagnosed patent ductus arteriosis by Echocardiographic examination

Exclusion Criteria:

• Accompanied other congenital cardiac anomalies

• Severe thrombocytopenia < 60.000

• Severe intracranial bleeding (Grade 3-4)

• Intestinal abnormality and necrotising enterocolitis