Overview

Efficacy and Safety of Nintedanib Combined With Paclitaxel Chemotherapy for Patients With BRAF wt Metastatic Melanoma

Status:
Completed
Trial end date:
2019-11-01
Target enrollment:
Participant gender:
Summary
This is a multicenter, randomized, double-blind, placebo-controlled phase I/II trial designed to characterize the safety and estimate the efficacy of nintedanib when combined with paclitaxel chemotherapy compared with paclitaxel chemotherapy alone in patients with BRAF wild type metastatic melanoma not previously treated with taxanes or kinase inhibitors.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Prof. Dr. med. Dirk Schadendorf
Collaborators:
Alcedis GmbH
Boehringer Ingelheim
medac GmbH
Treatments:
Albumin-Bound Paclitaxel
Nintedanib
Paclitaxel