Overview

Efficacy and Safety of MOX/ALB Co-administration

Status:
Active, not recruiting
Trial end date:
2021-12-01
Target enrollment:
Participant gender:
Summary
This study is a double-blind randomized controlled superiority trial aiming at providing evidence on the efficacy and safety of co-administered moxidectin and albendazole versus albendazole monotherapy (standard of care) against whipworm (T. trichiura) infections in adolescents and adults (12-60 years) in Côte d'Ivoire. One arm of patients will be treated with albendazole-ivermectin. As measure of efficacy of the treatment the cure rate (percentage of egg-positive subjects at baseline who become egg-negative after treatment) will be determined 14-21 days post-treatment.
Phase:
Phase 3
Details
Lead Sponsor:
Jennifer Keiser
Collaborator:
Centre Suisse de Recherches Scientifiques en Cote d'Ivoire
Treatments:
Albendazole
Ivermectin
Milbemycin
Moxidectin