Efficacy and Safety of Linggui Yangyuan Paste in Patients With Male Infertility
Status:
Not yet recruiting
Trial end date:
2024-12-01
Target enrollment:
Participant gender:
Summary
Male infertility affects millions of males worldwide and is rising in prevalence due to
social and environmental conditions. Asthenozoospermia (AZS) and oligoasthenozoospermia (OA)
are the major causes of male infertility. The diagnosis of male infertility has a negative
effect on men's physical and psychological status, poses a threat to their social
relationships, lowers self-esteem, and disrupts family harmony. At present, the treatment of
ASZ and OA are all mostly empirical, including antioxidants, endocrine therapy, and
anti-infection. However, there are still limitations due to inefficiencies. Linggui Yangyuan
paste (LGYY), a traditional Chinese compound herbal past, had been used to treat ASZ and OA
for several years at the Xiyuan Hospital of China Academy of Chinese Medical Sciences. The
investigators designed this program to study the efficacy and safety of LGYY for the
treatment of patients with male infertility (AZS and OA).
Phase:
Early Phase 1
Details
Lead Sponsor:
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Collaborators:
Chengdu Fifth People's Hospital First Teaching Hospital of Tianjin University of Traditional Chinese Medicine Shandong University of Traditional Chinese Medicine Shenzhen Traditional Chinese Medicine Hospital