Efficacy and Safety of Intravenous Paracetamol in Manament of Labour Pain

• Status: Completed
• Trial end date: 2020-05-10
• Target enrollment: 0
• Participant gender: Female

Summary

to compare between the use of single dose of paracetamol and pethidine hydrochloride intravenously in management of labour pains

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Menoufia University
• Treatments: Acetaminophen; Meperidine

Criteria

Inclusion Criteria:

• Primiparous

• aged 18-35 years,

• Term live singleton pregnancy,

• Vertex presentation,

• Spontaneous onset of labor at term 37-42 weeks gestation,

• In active phase of of 1st stage of labour (cervix dilatation 3- 4 cm).

Exclusion Criteria:

Clinical evidence of cephalopelvic disproportion

• Use of any kind of analgesia prior to study

• Any medical disorder during pregnancy (liver or kidney impairment)

• Induction of labor, Intrauterine fetal death

• Evidence of fetal distress

• Antenatal diagnosis of congenital malformation

• Previous history of hypersensitivity to either drug

• Extremes of age (i.e. below 18 or above 35)

• Multiple pregnancies

• Cervical dilatation more than 6 cm.