Efficacy and Safety of Intranasal Morphine for Pain After Bunion Surgery
Status:
Completed
Trial end date:
2005-08-01
Target enrollment:
Participant gender:
Summary
Study designed to evaluate the efficacy and safety of Intranasal (IN) Morphine Nasal Spray
(MNS075) 3.75 mg, 7.5 mg, 15 mg, and 30 mg, intravenous (IV) morphine 7.5 mg, or IN placebo
in patients with moderate to severe post-surgical pain following orthopedic surgery. After
initial dosing, up to six (6) doses of IN MNS075 7.5 mg or 15 mg for up to twenty-four (24)
hours will be evaluated. The rescue dose remained the same for each.