Overview
Efficacy and Safety of Increased Dose of TA-650(Infliximab) in Patients With Rheumatoid Arthritis
Status:
Completed
Completed
Trial end date:
2007-05-01
2007-05-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
The purpose of this study is to assess the efficacy, safety and pharmacokinetics of maintenance treatment with 3mg/kg, 6mg/kg or 10mg/kg of TA-650 in combination with methotrexate (MTX) after three infusions (weeks-0, 2, 6) of 3mg/kg in Rheumatoid Arthritis (RA) showing an insufficient response to MTX.Phase:
Phase 3Accepts Healthy Volunteers?
NoDetails
Lead Sponsor:
Mitsubishi Tanabe Pharma CorporationTreatments:
Infliximab
Criteria
Inclusion Criteria:- Patients with active RA in spite of stable dose of MTX
Exclusion Criteria:
- Having received infliximab in the past
- Having a history of serious infection which caused hospitalization within 6 months
before the registration
- Having an active tuberculosis
- Having a complication or a history of malignancy within 5 years before the
registration