Overview

Efficacy and Safety of Dapagliflozin in Acute Heart Failure

Status:
Recruiting
Trial end date:
2022-03-31
Target enrollment:
Participant gender:
Summary
This is a randomized trial of the addition of dapagliflozin to patients with diabetes hospitalized with acute decompensated heart failure (ADHF). Participants will be recruited following an initial standard evaluation in the ED and randomized within 24 hours of presentation for ADHF in a 1:1 fashion to protocolized diuretic therapy or dapagliflozin + protocolized diuretic therapy.
Phase:
Phase 3
Details
Lead Sponsor:
Vanderbilt University Medical Center
Collaborator:
AstraZeneca
Treatments:
2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol
Dapagliflozin
Diuretics
Sodium-Glucose Transporter 2 Inhibitors