Efficacy and Safety of Corticosteroids in Oxygen-dependent Patients With COVID-19 Pneumonia
Status:
Withdrawn
Trial end date:
2020-07-03
Target enrollment:
Participant gender:
Summary
To date, there is no efficient therapeutics to prevent or treat COVID-19 related pulmonary
failure. Corticosteroids (CS) could be a helpful therapeutic. Retrospective reports suggested
survival improvement in patients with acute respiratory distress syndrome (ARDS). CT scan for
COVID19 hospitalized patients showed sometimes unusual aspects of pneumonia, suggestive of an
organizing phase of diffuse alveolar damage (DAD).
We hypothesize that, in the context of alveolar aggression induced by COVID-19, CT scan could
help to individualize patients with a high probability of pulmonary organizing process who
could benefit from CS treatment.