Efficacy and Safety of Concomitant Use of Nevirapine and Rifampicin With HIV-TB
Status:
Completed
Trial end date:
2013-02-01
Target enrollment:
Participant gender:
Summary
The purpose of the study is to evaluate the efficacy and safety of Nevarapine and Rifampicin
vs Efavirenz and Rifampicin in antiretroviral naive patients co-infected with HIV and TB and
to investigate whether Rifampicin co-administration in clinical practice leads to a
clinically relevant decrease of Nevirapine plasma concentrations in Indian patients
co-infected with HIV and Tuberculosis and to characterize drug-associated toxicities
(especially hepatic).
Phase:
Phase 3
Details
Lead Sponsor:
All India Institute of Medical Sciences, New Delhi