Efficacy and Safety of Butorphanol Tartrate Injection for the Patients With Mechanical Ventilation

• Status: Not yet recruiting
• Trial end date: 2023-01-01
• Target enrollment: 0
• Participant gender: All

Summary

To compare the incidence of hospital-acquired infections between butorphanol and fentanyl.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shanghai Zhongshan Hospital
• Treatments: Butorphanol; Fentanyl

Criteria

Inclusion Criteria:

• need mechanical ventilation for more than 48 hours

• more than 18 years old

• without hospital-acquired infection before admission to ICU

• volunteer to participate in this study

Exclusion Criteria:

• allergic or contraindicated to the drug

• severe cardiac insufficiency, conduction block and bradycardia

• recent use of analgesic, sedative and antidepressant drugs

• psychiatric or neurological diseases or neurosurgery-related diseases

• history of steroid cortisol and immunosuppressants

• severe liver dysfunction or renal dysfunction

• pregnancy

• refuse to enrollment