Efficacy and Safety of Bupropion for Treatment of Adolescent Smoking

• Status: Terminated
• Trial end date: 2008-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine: 1) the short-term clinical efficacy and safety of bupropion for helping adolescent tobacco smokers quit, and 2) The role of withdrawal symptoms in the maintenance of smoking in adolescents.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: National Institute on Drug Abuse (NIDA)
• Treatments: Bupropion

Criteria

Inclusion Criteria:

• More than 100 lbs

• IQ greater than 80

• General good health

• Not pregnant

• Non-Smoker: No cigarettes in last 6 months, less than 5 in lifetime

• Smokers: Smoke more than 6 cigarettes per day for at least 6 months

Exclusion Criteria:

• Cardiac, Central Nervous System (CNS) or severe psychiatric disorder

• Psychoactive medications (including nicotine replacement)

• Substance use disorder