Efficacy and Safety of Ascending Doses of Arpraziquantel in Children Infected With Opisthorchis Viverrini
Status:
NOT_YET_RECRUITING
Trial end date:
2026-02-01
Target enrollment:
Participant gender:
Summary
This study aims to assess the efficacy, safety and acceptability of ascending doses of arpraziquantel compared to placebo in children infected with Opisthorchis viverrini. The primary objective is to determine the dose-response relationship in terms of cure rate. This study will involve children aged 2-7 years, since O. viverrini infections often occur in pre-school and school-aged children, and this group is largely left untreated in current public health programs.
Phase:
PHASE2
Details
Lead Sponsor:
Jennifer Keiser
Collaborator:
Lao Tropical and Public Health Institute (Lao TPHI)