Efficacy and Safety of AngongNiuhuang Pill in Patients With Acute Ischemic Stroke (ANGONG TRIAL)
Status:
Recruiting
Trial end date:
2021-10-30
Target enrollment:
Participant gender:
Summary
AngongNiuhuang pill has obvious effects on the cardiovascular and cerebrovascular diseases.
Pharmacological experiments confirmed that AngongNiuhuang pill can protect blood-brain
barrier, inhibit capillary permeability, improve the tolerance of cerebral ischemia and
hypoxia, reduce oxidative stress injury, thus protecting brain tissue. Clinical studies have
also confirmed that AngongNiuhuang pill can increase the GCS score, reduce coma, improve
nerve function defect and promote nerve function recovery. The primary purpose of this trial
was to evaluate the difference in the volume of cerebral infarction and cerebral edema
between Angong Niuhuang pill and placebo in patients with ischemic stroke at 14 days compared
with the baseline.