Overview

Efficacy & Safety for LN144 With Pembrolizumab With High Risk Stage IIIb-dResectable Melanoma

Status:
Suspended
Trial end date:
2028-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate the efficacy of adjuvant adoptive cell therapy (ACT) via infusion of LN-144 (autologous TIL) followed by interleukin-2 (IL-2) after a nonmyeloablative lymphodepletion (NMA-LD) preparative regimen, followed by Pembrolizumab.
Phase:
Phase 1
Details
Lead Sponsor:
James Isaacs, MD
Treatments:
Aldesleukin
Cyclophosphamide
Fludarabine
Interleukin-2
Pembrolizumab