Efficacy and Safety Study of Titrated Oral Misoprostol Solution for Labor Augmentation

• Status: Unknown status
• Trial end date: 2009-01-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to compare the efficacy and safety of titrated oral misoprostol solution with intravenous oxytocin for labor augmentation in women without adequate uterine contractions.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: China Medical University Hospital
• Treatments: Misoprostol; Oxytocin; Pharmaceutical Solutions

Criteria

Inclusion Criteria:

• Pregnancy between 36 and 42 weeks of gestation

• Live singleton

• Cephalic presentation

• A reassuring fetal heart rate pattern

• Bishop score greater than 6

• Inadequate uterine contraction (less than or equal to 2 per 10 minutes)

Exclusion Criteria:

• Nonreassuring fetal heart rate pattern

• Parity more than five

• Uterine scar

• Suspected placental abruption with abnormal fetal heart rate

• Vaginal bleeding other than "bloody show"

• Significant maternal cardiac, renal, or hepatic disease

• hypersensitivity to oxytocin, misoprostol or prostaglandin analogues