Efficacy and Safety Study of Tesamorelin in Chronic Obstructive Pulmonary Disease (COPD) Subjects With Muscle Wasting
Status:
Terminated
Trial end date:
2011-12-01
Target enrollment:
Participant gender:
Summary
A significant proportion of COPD subjects experience muscle wasting, which has been
associated with increased morbidity, impaired physical functioning, and a poor quality of
life.
Muscle wasting is associated with reduced muscle strength in COPD subjects. In particular,
weakness of peripheral muscles has been reported to play an important role in the reduced
functional capacity and impaired exercise performance.
The primary objective of this study is to investigate the effect of tesamorelin, in
conjunction with exercise training, on lean body mass measured by dual energy x-ray
absorptiometry (DXA) scan.