Efficacy and Safety Study of Avastin to Treat Neovascularisation of the Cornea
Status:
Completed
Trial end date:
2019-10-01
Target enrollment:
Participant gender:
Summary
Corneal newvessels may arise from a fan of pathologies, inducing long-standing corneal
opacification requiring keratoplasty. These last years, VEGF inhibitors have been designed to
reduce newascularization induced by gastric cancer or age-related macular degeneration. A few
reports have been published showing the interest of VEGF inhibitors to treat corneal
newvessels, but no randomized study has been achieved to date.
This study is designed to assess the efficacy of Bevacizumab, a VEGF inhibitor monoclonal
antibody, to reduce the surface of corneal newvessels in when compared to placebo